![]() ![]() Concurrent neutrophilic inflammation which may be septic is common. Cells exhibit a high nuclear-to-cytoplasmic ratio, mild to marked anisocytosis and anisokaryosis, and small condensed or larger oval vesicular nuclei with prominent nucleoli, +/- prominent perinuclear vacuolation. Medium to large, oval/round to angular epithelial cells occur singly and in sheets. Solitary or multiple, plaque-like or raised proliferative or ulcerative masses often on pinnae or face. Melanin pigment may be present within the cells or in background with cystic amorphous blue material and degenerate cells. Cytologic Characteristics of Cutaneous/Subcutaneous Discrete Round Cell Tumors TypeĬohesive aggregates of small basaloid epithelial cells with high nuclear-to-cytoplasmic ratios, scant blue cytoplasm and monomorphic round to oval nuclei. Table 1 provides a summary of cytologic features and typical locations for each round cell tumor type. 2 In this color atlas, cytologic characteristics of the four most common skin tumors will be reviewed. The ten most common skin tumor types accounted for 80.7% of cases, with the four most common being basilar epithelial tumor, fibrosarcoma, squamous cell carcinoma and mast cell tumor. In a retrospective study of more than 9,000 feline cutaneous tumors, 6.6% were non-neoplastic and 93.4% were neoplastic, of which 52.7% were considered malignant. Samples can often be collected, prepared and evaluated microscopically in a matter of minutes. Sedation or anesthesia is rarely needed for sample collection. 1 The results of cytologic evaluation may provide information about prognosis, guidance for next diagnostic steps and/or treatment. In one study comparing cytologic and histopathologic test results of cutaneous and subcutaneous lesions in 243 specimens from cats and dogs, the diagnosis was in agreement in 90.9% of cases. Veterinary Clinic for Low Income Pet OwnersĬytologic evaluation of feline cutaneous mass aspirates is a convenient, rapid way of obtaining a definitive or presumptive diagnosis in a majority of patients.Vet Services Report Cruelty Animal Advocacy Adopt ![]()
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